Marilyn Hardesty is an aging horror film actress, and heiress to her ancient husband's biotech fortune through a whirlwind courtship, marriage, and funeral. Terminally ill, she is determined to cheat death and rekindle her career by transferring her mind into the body of a younger woman. With Norman Baetz, her "personal assistant", she recruits Dr. Laurence Fine, a brilliant, twisted neurobiologist, to serve her obsession with immortality.
With the promise of Reality TV stardom, they lure three young women to Marilyn's remote estate. Ulterior motives unfold. Early experiments prowl the estate. The young women reach a grim realization: escape is the only means of survival. Can they evade Dr. Fine's cut and paste cybernetics? Will Marilyn achieve eternal life or drown in the fountain of youth?